Thiosinaminum

A chemical compound derived from mustard oil (allyl thiourea), formed by the combination of mustard oil and ammonia. It is a sulphur-containing compound used in both allopathic and homeopathic spheres for its antifibrotic action.

No extensive classical proving; largely developed through clinical observation and toxicological effects. Most data come from therapeutic use in low potencies.

• Complementary: Silicea, Calcarea fluorica, Graphites
• Antidotes: Unknown
• Follows well: After constitutional treatment, as a resolving agent
• Precedes well: Nosodes or deeper acting miasmatic remedies once scars soften
• Inimical: No known inimicals

• Connective tissues – scar tissue, adhesions, fibrotic formations
• Glands – fibrotic degeneration, tumours
• Female reproductive system – uterine fibroids, fallopian tube adhesions
• Ear – hearing loss from fibrotic otitis or middle ear sclerosis
• Skin – thickened scars, keloids, contracted skin
• Serous membranes – pleura, peritoneum, post-inflammatory adhesions

Limited information. Clinical observation suggests some sluggishness or apathy in long-standing sclerotic states. Patients with chronic complaints and long-term suppression may show mental dullness, fatigue, or frustration at lack of progress.

No marked symptoms, but improvement in chronic cases may restore restful sleep.

Thiosinaminum is a slow-acting remedy, suited to long-standing, fibrotic, adhesive, and indurated conditions. It has a strong affinity for scar tissue, both internal and external. Particularly useful after surgery, injury, or chronic inflammation that resulted in abnormal thickening or contraction of tissues. Best given in low potencies over time, sometimes with topical application or low trituration. Often used in alternation with constitutional or deeper-acting remedies.

Not an acute remedy for fever. However, may be useful in post-febrile sequelae like pleural thickening or lymphadenopathy.

Limited information. Clinical observation suggests some sluggishness or apathy in long-standing sclerotic states. Patients with chronic complaints and long-term suppression may show mental dullness, fatigue, or frustration at lack of progress.

Limited information. Clinical observation suggests some sluggishness or apathy in long-standing sclerotic states. Patients with chronic complaints and long-term suppression may show mental dullness, fatigue, or frustration at lack of progress.

Effective in adhesive otitis media with thickened tympanic membrane or ossicular sclerosis. Useful in hearing loss following middle ear fibrosis. May improve chronic eustachian tube obstruction due to scar tissue [Boericke].

Rare usage. Potential utility in post-inflammatory nasal adhesions. Dryness or obstruction from nasal scarring.

Not directly indicated. However, may aid in post-surgical facial scars, acne scars, or contractures around jaw following trauma or operation.

Occasional aphthae or fibrotic oral ulcers. Dryness or loss of flexibility of tissues post-radiation or post-surgical intervention. Clinically may support scarred tissue inside the mouth or after dental surgery.

Thickening of pharyngeal mucosa or post-inflammatory strictures of oesophagus or larynx. Cases of laryngeal stenosis and vocal cord scarring post-infection have reportedly improved with Thiosinaminum.

Acts on pleural thickening, post-tubercular or post-pneumonic adhesions. Assists in restoring elasticity to the chest wall. Dyspnoea or chest restriction due to fibrous bands.

Rarely indicated directly. Theoretically useful in pericardial adhesions or post-inflammatory thickening of heart membranes.

Dyspnoea from fibrotic restriction of thorax. Used in fibrotic asthma, pleural scarring, or chronic bronchitis with emphysema-like changes.

Limited use. Possibly indicated in gastric wall fibrosis, post-ulcer scarring, or old strictures. Not a general remedy for digestive complaints.

Not used in general dyspepsia but helpful in post-surgical adhesions, especially involving the peritoneum. Scar tissue after abdominal surgeries or infections like appendicitis, peritonitis, or PID are core indications.

Indicated in anal or rectal strictures, post-fissure or fistula surgery. Chronic constipation from scarring or muscular inflexibility. Useful for post-haemorrhoidectomy fibrosis.

May support treatment of urethral stricture, especially post-surgical or post-infective. Some evidence for benefit in bladder wall fibrosis or loss of compliance after radiation.

No cravings or aversions noted.

Helpful in strictures of vas deferens, testicular fibrotic nodules, or post-infectious adhesions following epididymo-orchitis. Not commonly used for general sexual symptoms.

Highly indicated in uterine fibroids, pelvic adhesions, and tubal blockage from post-infectious or post-surgical fibrosis. Suited for infertility where adhesions are known. Also used in ovarian induration or post-Caesarean scar tissue [Boericke].

Pain from scarred or fibrosed tissue in paraspinal musculature. Useful in old injuries with contraction of back muscles or ligaments.

Stiffness from contracted tendons, ligaments, or joints after surgery or injury. Indicated in Dupuytren’s contracture, post-traumatic joint adhesions, and fibrotic thickening around knees or ankles.

A major remedy for keloids, scars, adhesions, and contractures. Scar tissue becomes lighter, flatter, and more flexible. Also effective in post-burn fibrosis, post-operative scars, and acne scarring. May reduce thickening and nodularity over time. Skin feels tight and restricted.

• Fluoric acid – Scar tendency with destructive degenerative processes; more suited to varicosities and long-standing ulcers
• Silicea – Scar and induration with suppuration or foreign body rejection; deeper miasmatic action
• Calcarea fluorica – For hard, stony nodules, bony outgrowths, and fibrous swellings
• Graphites – Scarred skin with tendency to eczema or discharge; thicker skin and more skin-related pathologies
• Causticum – Contractures from nerve damage; suits post-paralysis better than fibrotic scarring

• Complementary: Silicea, Calcarea fluorica, Graphites
• Antidotes: Unknown
• Follows well: After constitutional treatment, as a resolving agent
• Precedes well: Nosodes or deeper acting miasmatic remedies once scars soften
• Inimical: No known inimicals

• Especially useful in post-operative adhesions (abdomen, pelvis, joints)
• Excellent for keloids, post-acne scars, and burn contractures
• Indicated in female infertility from fallopian adhesions
• May improve hearing loss from middle ear sclerosis
• Use in low potencies (3X to 6X) over extended periods; gentle action builds cumulatively
• Combine with constitutional remedy for long-term correction

Skin

• Keloids
• Scars, indurated
• Scars, contractures
• Scars, acne, after
• Scars, from burns

Extremities

• Contractures, post-injury
• Stiffness, after injury
• Joints, adhesions in

Female Sexual Organs

• Adhesions, fallopian tubes
• Uterus, fibroid
• Sterility, from tubal blockage

Ear

• Hearing loss, fibrotic
• Otitis media, chronic, with sclerosis

Generalities

• Adhesions, post-surgical
• Induration, fibrotic
• Scars, internal organs

• William Boericke – Pocket Manual of Homeopathic Materia Medica: Provided core clinical indications for fibrous tissue, uterine fibroids, and adhesions
• Clarke – Dictionary of Practical Materia Medica: Confirmed use in contractures, scars, keloids
• J.H. Clarke – Prescriber’s Manual: Application to infertility and strictures
• Practical Homeopathy (Modern Clinical Sources): Cases documenting post-operative recovery and skin healing
• H. Roberts – Sensations As If (partial references): For sensations of tightness and constriction in scar regions