• Connective tissue: nails, bones, joints, ligaments, skin
• Lymphatic and glandular system: chronic suppuration, abscesses
• Nervous system: fatigue, chilliness, oversensitivity
• Mind: timidity, indecisiveness, performance anxiety
• Feet and extremities: offensive sweat, weakness
• Spine and meninges: scoliosis, neuralgia, slow development in children
• Left side and lower right quadrant (e.g., right inguinal region)

• Warmth, especially warmth of bed [Kent]
• Wrapping up, especially head and feet
• Summer, and warm, dry weather
• Lying on painful side (oddly relieves)
• Profuse perspiration, which relieves symptoms
• Discharging, especially abscesses, boils, or ear discharges
• Constancy and routine (emotionally stabilising)

• Cold, drafts, uncovering, especially of head or feet [Clarke]
• Full moon (mental and physical aggravation)
• Suppression of sweat, eruptions, or discharges
• Vaccination, especially if chronic symptoms followed
• Mental exertion, study, or anticipation
• Milk, often disagrees
• Change of weather, especially from warm to cold
• Exams, performances, interviews (anticipatory anxiety)

Silicea individuals are often delicate, sensitive, and highly conscientious, with deep-seated insecurity. They are prone to chronic fear of failure, public speaking, or being judged. There is mental weakness, particularly from overexertion, yet they may be quietly determined, even obstinate. Despite timidity, once committed, they display a slow but persistent will [Kent]. They are often emotionally fragile, feeling overwhelmed by responsibility. Lack of confidence, especially in decision-making or asserting opinions, is prominent. Easily discouraged, weepy when confronted. Marked anticipatory anxiety, especially before public events or exams, which may even cause diarrhoea [Boericke].

Headaches begin in occiput and travel to forehead or eyes, often due to mental exertion or suppressed discharges. Sensation of pressure, as from a band or a weight on the vertex. Open fontanelles in children; skull development slow. Perspiration of scalp, especially at night, with a sour odour. Hair thin, dull, and falls out easily. Vertigo from motion or fasting. Chronic sinusitis with forehead pressure and blockage [Clarke].