• Respiratory mucosa (especially chronic catarrh and ulcerations).
• Skin (chronic eczema, psoriasis, ulcerations, exfoliations).
• Lymphatic glands (enlargement, induration).
• Nutrition and metabolism (marasmus, wasting diseases).
• Cardiovascular system (weakness, palpitations in chronic states).
• Mucous membranes of digestive tract (chronic gastritis, ulcer tendency).

• Warmth and warm surroundings, though less marked than pure Arsenicum album.
• Fresh air in some chronic catarrhal states.
• Gentle movement during exhaustion phases.
• Improvement in summer in some skin conditions.

• Cold, damp air.
• Night, particularly after midnight.
• Change of season, especially spring and autumn.
• Physical exertion when weakened.
• Suppressed discharges (nasal, skin) leading to internal aggravations.

The mental state of Arsenicum iodatum combines the restlessness and anxiety of Arsenicum album with the hurried, driven quality of <a href="https://www.iqhomeopathy.com/materia-medica/iodum/">iodine. Patients are often thin, nervous, and overactive until collapse, when profound weakness and despondency set in. There is a fear of impending disease and an impression of wasting away despite eating. Restlessness is less frantic than in Ars. alb., but there is a persistent drive to move or work, even when exhausted [Farrington]. Irritability arises from the discomfort of chronic discharges, and there is a tendency to be overly critical or dissatisfied. Melancholy appears during prolonged illness, especially tuberculosis or wasting skin disease.

Headaches are often associated with chronic nasal catarrh or sinusitis, with a dull, heavy feeling in the frontal sinuses. There may be a burning heat in the forehead, worse at night and in a warm room, better in cool air. In wasting diseases, the head may sweat easily, especially in the occipital region. Vertigo appears on rising suddenly or during catarrhal blockage of the nose.