Malandrinum stands as a sycotic nosode whose signature is hyperkeratosis plus fissuring, set against a background of suppression and vaccinosis. The patient’s story is classic: after vaccination or years of local salving, the skin becomes coarser, drier, more warty, and prone to cracking—at the margins (lips, nostrils, anus, vulva) and extremities (fingertips, heels, peri-ungual folds). Each contact with water, particularly cold water, restarts the cycle: splits open, bleeds, crusts, then splits again. The person adapts—gloves, greasy emollients, avoidance of washing—and the mind grows resigned, a touch irritable, bound to regimens that palliate but never cure. This is the sycotic logic: outward disease forced inwards returns as overgrowth (warts, corns), thick scaling, and indurated nodes, while the organism shows seasonal dependence—winter/damp brings relapse, dry warmth brings reprieve.

As a nosode, Malandrinum often works intercurrently, removing a miasmatic obstacle that has made well-chosen remedies stall. It is smaller than Thuja or Sulphur but sharper in the fissure–warty–washing triad. Thuja may dominate when vegetations and genito-urinary traits lead; Sulphur when burning/itching and standing heat colour the whole. Graphites governs the sticky, honey-oosing eczema and soft crusts; Petroleum the oily, nauseated, winter-cracked patient. Malandrinum sits where the skin is dry, splitting, and keratinised, washing aggravates, and the history of vaccination or local suppression is compelling. Its action is felt as the skin softens and knits, the need for constant salving recedes, and constitutional remedies hold once more. In this sense Malandrinum is less a “star” and more a key, turning the case toward resolution by restoring proper elimination through the skin and curbing the sycotic drift to overgrowth and induration [Burnett], [Clarke], [Boericke].

Medorrhinum is the surge of sycosis—a tide of excess and oscillation. On the surface, sycosis overgrows: warts, mucous patches, oily skin, thick green/yellow secretions, fish-odour discharges, profuse leucorrhoea; inside, it infiltrates tissues—the prostate thickens, the cervix indurates, the ovary cysts, peri-articular tissues swell. Functionally, the patient swings: constipation ↔ diarrhoea, insomnia ↔ night elation, apathy ↔ reckless vivacity, impotence ↔ satyriasis—the diathesis of too much and too little alternating. The nervous system shows hurry, impulsiveness, time distortion, aphasic forgetfulness of names/what was just said, and hypervigilance (“someone behind me”), which resonates with an evolutionary memory of pursuit; this spills into dream-life (pursuit, serpents, obscene scenes) and night attacks (2–4 a.m. asthma, palpitations, sweats). The body seeks positions that unload congestion—knee-chest, face-down, limbs flung out, feet uncovered/fanned—revealing the organ axes (chest, back, soles). Place modifies fate: seaside usually ameliorates lungs, joints, skin (salt, sun, steady breeze), while damp inland oppresses, spawning catarrh, rheumatism, and mental gloom. Time is nocturnal: night brings excitement, libido, fantasy, and also terrors; day is heavy, forgetful, irritable.

In a clinic narrative, Medorrhinum often appears behind multi-system churn in patients or families with gonorrhoeal history or sycotic traits: warts, recurrent otorrhoea, adenoids, glue ear, asthma, eczema, enuresis, precocious sexuality, left ovarian pains, post-gonorrhoeal prostate/urethra. The modalities are vivid: seaside >, damp <, 2–4 a.m. <, heat of bed (feet) <, lying prone and knee-chest >; the cravings (ice-cold drinks, oranges, salt/sour) and thermal paradox (hot feet, cold hands) knot together with memory lapses and night exhilaration to forge a composite that is hard to miss once seen. Where Thuja is inward, controlled, brittle, chilly and suspicious, Medorrhinum is outward, reckless, hot-footed, night-thrilled, and seaside-seeking; where Sulphur philosophises amidst ragged heat, Medorrhinum hurries amidst sticky excess.

Therapeutically, Medorrhinum does not merely “antagonise gonorrhoea”; it regulates the sycotic field, reopening suppressed outlets (skin, mucus) and quieting nocturnal overdrive. In chronics, intercurrent use can untie knots before organ-specific remedies (e.g., Sep., Kali-s., Sars.) take hold. Attend to environment (dehumidify inland homes, encourage coastal air/sea-bathing when appropriate), sleep posture (permit prone/knee-chest), and foot cooling (cotton sheets, fan the feet)—small measures that echo the remedy’s language and accelerate cure. [Hering], [Kent], [Clarke], [Allen], [Boger], [Boericke], [Tyler], [Phatak], [Nash], [Farrington], [Lippe], [Dunham]

The essence of Morgan Bach is that of an over-loaded, over-suppressed, over-fed terrain whose primary excretory routes—bowel, skin, portal–venous system—are struggling under the weight of diet, drugs, and chronic miasms. Bach’s composite Morgan bacilli represent a microbiome that has adapted to this inner milieu: fermentation, putrefaction, mucous thickening, and toxic metabolite production in the large intestine. The nosode Morg. is therefore less about a single microbe than a symbolic signature of a whole congestive ecosystem, expressing itself through IBS, haemorrhoids, eczema/psoriasis, and “toxic mornings”. [Bach], [Paterson], [Julian], [Mendonca]

Psychologically, these patients reflect their inner state. They are often sulphuric—hot, opinionated, irritable, self-critical—but in a specifically Morgan Bach way: preoccupied with detox, diets, and “rubbish in the system”, angry at themselves for lapses, angry at others for not understanding, and ashamed of their skin or weight. They may read widely, experiment with radical regimes, and post about health theories, yet struggle to implement simple, durable changes such as regular walking, earlier nights, and moderate eating. This is the psoric–sycotic polarity: restless mind, push towards overdoing, paired with chronic, fixed congestion in tissues. [Julian], [Templeton]

Thermally and sensorially, Morg. is hot and reactive: worse from heat and stuffy rooms, better in fresh, cool air, yet often comforted by mild warmth around body. Skin and veins protest in heat: eczema flares, psoriasis thickens, veins bulge, haemorrhoids burn. Sleep is fragmented by itch, heat, and bowel urgency. Mornings are “toxic”—heavy head, foul taste, coated tongue—until stool and movement clear some of the load. This pattern is repeated across Head, Mouth, Abdomen, Rectum, Skin, Sleep, and Generalities.

Miasmatically, the remedy stands at a crossroads of psora, sycosis, and syphilis with tubercular hints. Psora supplies itch, anxiety, and functional hyperreactivity; sycosis adds overgrowth, chronicity, and a tendency to repeated, unresolving inflammatory cycles (eczema–steroid–eczema, IBS–antibiotics–IBS); syphilis appears in fissures, ulcerations, and degenerative colitis; tubercular colour emerges in restless, travel-seeking Morg. subjects who oscillate between trying many therapies and lapsing into excess and self-neglect. [Paterson], [Boyd], [Mendonca]

The key polarity is over-abundance vs elimination: the person is not starved; they are overloaded—with food, drugs, toxins, suppressed discharges, resentments. The organism fights to keep exits open (bowel, skin, sweat, menses), but each suppression or indulgence adds to the internal burden. Morgan Bach’s role is to re-educate the terrain: to shift the bacterial–immunological ecology so that elimination becomes more orderly, less inflamed, and more sustainable. In practice, after Morg. one often sees a re-organisation of eruptions and stool: sometimes a brief, manageable aggravation; then more regular stools, less explosive diarrhoea, more stable skin with milder flares, and a cooling of the temperament. [Julian], [Agrawal], [Gupta], [Templeton]

Crucially, Morg. must be distinguished from its daughter nosodes. Morgan pure shares the sulphuric heat and psoriasis but is narrower, often aligning with deep, stubborn psoriatic diathesis where plaques are the central drama and stool cultures show the pure Morgan strain; Morgan Gaertner belongs more to thin, under-assimilating Gaertner-like patients, where mixed Gaertner–Morgan features appear biochemically and clinically (failure to thrive, recurrent infections). Morgan Bach remains the broad, Bach-level composite: the nosode for the many patients whose liver, bowel, skin, and veins all shout “Morgan” but cannot be neatly filed under pure or Gaertner. [Paterson], [Julian]

In clinical practice, Morg. is rarely a lone actor. It usually plays in an ensemble: with Sulph., Nux-v., Lyc., Sep., and others; with Morgan-p., Morgan-G., Gaertn., Psor., Med., Tub., Carc. As a first intervention at the bowel–liver level, it often softens, clarifies, and reduces the risk of severe aggravations when deeper miasmatic remedies are later required. For the homeopath attuned to microbiome–terrain thinking, Morg. is a keystone nosode: a way to speak to the overloaded Morgan ecosystem and invite it back toward a more harmonious balance.

The essence of Morgan Gaertner is that of a delicate, under-assimilating, tubercular Morgan–Gaertner terrain: a person who takes in more than they can build with, whose microbiome has shifted from the dense, congested Morgan Bach composite toward the dynamic, unstable Gaertner pattern, and whose life story is one of frequent infections, poor growth, and fragile resilience.

Where Morgan Bach represents the over-loaded Sulphur–Morgan type—heavy, heat-intolerant, congested, with eczema–psoriasis and piles—and Morg-p. the deep psoriatic Morgan type—plaque psoriasis, colitis, arthropathy—Morg-g. stands for those whose Morgan heritage is expressed as lack rather than surplus. They are thin, pale, quick in mind but short in stamina, emotionally sensitive and easily worried, and physically pushed around by every cold, exam, or dietary upset. [Paterson], [Julian], [Mendonca]

The central polarity is activity vs reserves. These individuals often possess bright minds, imagination, and a desire to participate; children want to run and play like others; adults want to work and socialise fully. But their reserves are low: a single day of over-activity or excitement may be followed by hours or days of collapse—headache, tummy ache, fatigue, or an infection. This pattern recurs across Head, Abdomen, Chest, Sleep, and Generalities. The bowel—especially small intestine—is like a half-sized factory: food passes through, but extraction of nutrients is incomplete; the system runs on fumes.

Miasmatically, Morg-g. is distinctly tubercular: recurrent infections, alternating states, restlessness, and desire for change. Psora contributes the sensory and functional hypersensitivity—food intolerances, IBS, headaches, anxiety; sycosis keeps the pattern repeating across years; syphilitic tendencies lurk in the background when under-nutrition and chronic inflammation erode tissues or bones. [Boyd], [Mendonca] The microbiome signature—Morgan bacilli acquiring Gaertner features—gives a biological mirror to this story: a flora that has shifted from the heavy Morgan of Bach toward the more unstable, growth-impairing Gaertner.

In practice, Morg-g. is seen in:

• Children who fail to thrive despite apparently adequate diet, who are pale, thin, frequently ill, and slow to regain weight after each infection.
• Adolescents with chronic fatigue, IBS, and recurrent sinusitis or bronchitis, who struggle to keep up with school and sport, and who worry about underperformance.
• Adults with post-viral fatigue, IBS, and low-grade recurrent infections, who cannot tolerate strong exercise programmes and relapse after each “push”.

Crucially, Morg-g. is not just “a weak child remedy”: underneath the frailty is often a strong mental spark and a strong tubercular miasm. When the intestinal terrain is addressed—often with Morg-g. alongside supportive diet and constitutional remedies—these individuals can build a much more stable platform of health on which their talents can express more fully.

The contrast with the other Morgans must be kept clear:

• If a case is dominated by broad, congestive Morgan features (over-weight, eczema/psoriasis, IBS, haemorrhoids, heat aggravation, over-eating), think first of Morgan Bach.
• If the story is one of thick, plaque psoriasis, colitis, and arthropathy in a reasonably built person, think Morgan pure.
• If the core is failure to thrive, recurrent infections, malassimilation, nervous exhaustion in a thin person, and the history or stool pattern says “Morgan–Gaertner”, think Morg-g.

Used wisely, Morg-g. rarely acts alone. It sits in a therapeutic network: with Gaertn. and Tub. for the tubercular and assimilative axis; with Sil., Phos., Calc-phos. for growth and bone; with constitutional remedies such as Lyc., Sulph., Nat-m., Puls., or Phos. as the psychological and constitutional core demands. Its specific gift is to renegotiate the Morgan–Gaertner microbiome pattern, improving assimilation and immune resilience, so that the organism is no longer knocked flat by every stressor.

The essence of Morgan pure is the refined psoriatic Morgan terrain: a human organism whose intestinal microbiome, immune system, and integument have settled into a pattern of chronic, thick, plaque-like over-expression. The Morgan pure strain, selected from the broader Morgan group, mirrors this pattern: a stable, persistent micro-organism whose biochemical profile remains constant across subcultures. As the microbe refines itself, so does the terrain: psoriasis solidifies from eczema-like flux into persistent plaques; IBS hardens into chronic colitis; joint pains coalesce into recognisable psoriatic arthropathy. [Paterson], [Julian], [Mendonca]

Psychologically, Morg-p. patients carry the story of long siege. Many have suffered from psoriasis since childhood or adolescence, and from bowel issues for years. They have gone through cycles of hope and disappointment with creams, diets, and drugs. They are tired of being seen and not seen—visible because of lesions, invisible in their deeper distress. Irritability, sarcasm, and bitter humour act as armour against humiliation and repeated medical failures. They are not apathetic; they are tenacious fighters worn thin by chronic war with their own body. [Julian], [Templeton]

This remedy’s central polarity is persistence vs flow. Plaques persist. Inflammation persists. Patterns persist: same lesions, same triggers, same relapses. The organism cannot easily flow—bowel movements may be obstructed or inflamed; joints stiffen; mental and emotional patterns calcify. Heat, suppression, and stress drive processes further into rigidity and destruction. Morg-p. is indicated when this frozen psoriatic language of the body is clearly linked to the Morgan pure intestinal terrain, not just to generic psora.

Miasmatically, the psoric–sycotic imprint is unmistakable: psora gives itch, hypersensitivity, and over-reactive mucosae; sycosis contributes chronic thickening, plaque formation, venous congestion, and unending reproduction of inflammatory foci. Syphilitic under-tones—ulceration, joint erosion, mucosal bleeding—emerge as the disease runs long and deep. Tubercular hints appear in restlessness, changes of therapy, and occasional dramatic flares. [Paterson], [Boyd], [Mendonca]

Where Morgan Bach addresses a broad, mixed Morgan ecosystem—eczema, IBS, piles, mixed skin—Morg-p. addresses the refined, intensified psoriatic Morgan pure sub-ecosystem. It is as though the organism, under years of selection pressure (diet, drugs, stress), has sharpened its pathological language into a more insistent script: thick plaques, colitis, arthropathy. Morg-p. speaks to that sharpened language.

In clinical practice, the essence of Morg-p. appears in patients whose disease has outgrown broad, generic approaches. Sulph., Nux-v., Lyc., Morg., and other polychrests and nosodes may have helped, but a stubborn core remains: classical plaque psoriasis, chronic colitis, sacroiliac and peripheral arthritis, nail pitting. This is where Morg-p., introduced carefully, can shift the terrain. One often sees an initial phase of re-organisation: some plaques soften, others reduce in thickness, bowel movements become somewhat more coherent, joint pains fluctuate. If the remedy is well chosen and not over-used, a deeper phase follows: fewer flares, shorter duration, less severity; periods of almost-clear skin; improved mobility; less drug dependency. [Julian], [Agrawal], [Gupta], [Templeton], [Mendonca]

Importantly, Morg-p. should never be seen as a magic bullet for psoriasis but as a terrain lever. It works best when accompanied by sensible changes: reduction of known triggers, gentle regular exercise, good sleep hygiene, and gradual, well-supervised adjustment of suppressive medications in collaboration with medical care. Its true essence is re-negotiation: between the organism and its Morgan pure microbiome; between immune system and skin; between patient and their long history of treatment. When that negotiation becomes more balanced, plaques and colitis become less tyrannical, and the individual can live with far less daily suffering.

Mutabile represents a subtle but powerful layer in the evolution of chronic atopic and dysbiotic disease. Its essence lies in the word that names it—changeability—and in the intermediate position it occupies between B. coli and the Morgan group, between simple coliform saprophytes and more clearly pathological bowel flora. Clinically, this translates into patients whose symptoms never truly settle, whose disease picture refuses to crystallise in one organ or one classical remedy, and whose life history is dominated by alternating skin, respiratory, bowel and urinary complaints against a background of emotional dependency and environmental sensitivity.

Psychologically, Mutabile patients (often children or young adults) resemble Pulsatilla: gentle, easily moved to tears, seeking affection and reassurance, improved by cool open air and by the presence of supportive people. They dislike heat and stuffy rooms; they are timid in new situations but crave company. Yet, whereas Pulsatilla alone may cure early phases of such constitutions, the Mutabile patient has often passed through a more complex journey: repeated antibiotics, steroid creams, vaccinations, and modern environmental burdens have altered the bowel flora and immune system, giving rise to a deeper, nosodic layer. The organism responds to this disturbance with a kind of internal restlessness: when one outlet is blocked, another opens; when skin is suppressed, lungs speak; when bowels are quieted, kidneys or joints take over.

Miasmatically, Mutabile belongs in the psoro-sycotic–tubercular spectrum. Psora contributes the allergic reactivity, itching, functional disturbances and emotional dependency; sycosis underlies the proliferative, mucous, catarrhal and structural (diverticulum, hypertrophy) manifestations; the tubercular element reveals itself in the constant urge to change, the sensitivity to weather and environment, and the alternating, shifting nature of pathology. Unlike deeply destructive syphilitic remedies, Mutabile expresses the organism’s attempt to adapt, to move the burden from vital organs to less vital, then back again when outlets are closed.

The essence could be summarised as “the atopic Pulsatilla of the bowel nosode world.” When a kind, soft, weeping Puls. or Ferr-phos. child presents with long histories of eczema, asthma, otitis, allergies and digestive upsets that have swapped places for years, and when conventional treatments have suppressed one only to see others rise, Mutabile deserves serious consideration. It is not a substitute for constitutional prescribing but a bridge: it restores a degree of order to the terrain, helping the immune system and flora re-establish a healthier relationship, so that classical remedies can act more predictably.

In practice, you may see Mutabile’s essence in the child whose eczema cleared quickly with steroid creams only to develop asthma; whose asthma was controlled with inhalers only to develop nephritic changes; whose nephritic picture was managed with orthodox drugs only for chronic colitis or IBS to appear. All along, the emotional tone remained Puls-like: gentle, needy, better with comfort and cool air. Or in the adult whose life story is one of shifting complaints across skin, sinuses, lungs, gut and urinary tract, each phase triggered by diet, stress or environmental shifts, with stool cultures repeatedly revealing coliform anomalies and poor diversity of flora. For such patients, Mutabile acts as a catalyst to reinstate older symptoms (especially safer outlets like skin), reduce dangerous alternations, and allow a clear constitutional portrait to emerge.

The pace of Mutabile is subacute to chronic; it does not act at lightning speed like Acon. or Bell., but over weeks and months you see a re-ordering. Old skin lesions may reappear; asthma attacks may lessen in frequency and severity; albuminuria may decrease as the organism chooses safer avenues. When this occurs, one must resist the temptation to suppress the returning skin, recognising instead that the case is moving in a Heringian direction. The essence of Mutabile is thus intimately linked with Hering’s Law: it encourages the vital force to re-adopt more peripheral, less dangerous expressions of disease in an organism whose defence has been distorted by gut dysbiosis and suppression.