Marsdenia condurango

Latin name: Marsdenia condurang

Short name: Condur

Common name: Condurango Bark | Cundurango Vine | Eagle Vine | Condor Vine | Andean Bitter Bark

Primary miasm: Syphilitic   Secondary miasm(s): Psoric, Sycotic

Kingdom: Plants

Family: Apocynaceae (Asclepiadoideae)

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  • Symptomatology
  • Remedy Information
  • Differentiation & Application

Condurango is the dried bark of an Andean climbing vine (Apocynaceae, subfamily Asclepiadoideae) native to Ecuador, Peru, and Colombia. The bark contains a bitter principle historically named “cundurangin,” with resins and allied constituents typical of Apocynaceous bitters; these explain much of the gastric stimulation and epithelial action seen clinically and in provings [Hughes], [Clarke]. In crude form it may provoke burning from the fauces to the epigastrium, nausea, and altered appetite [Toxicology—Hughes]. In homœopathy, the mother tincture is prepared from carefully dried, coarsely powdered bark macerated in strong alcohol; potencies are prepared by centesimal dilution and succussion per pharmacopœial standards [Clarke], [Boericke]. Classical writers repeatedly emphasise its affinity for mucocutaneous junctions (angles of mouth, nipples, anus), the oesophagus and cardia, and chronic indolent ulcers with callous edges—an epithelial signature that threads through its entire picture [Hering], [Allen].

Brought to Europe and North America in the early 1870s with claims from Ecuadorian practice as a “cancer remedy,” it was widely tested as a bitter stomachic and vulnerary for chronic gastric catarrh, ulcerations, and fissured skin or mucosa. Eclectic and orthodox physicians prescribed decoctions and tinctures for dyspepsia, aphthous or syphilitic ulcerations, and oesophageal stricture; later assessments tempered early enthusiasm but retained its value as a tonic bitter and epithelial healer [Hughes], [Clarke].

Introduced to homœopathy in the United States (New York) soon after 1871; provings recorded by Dowling and colleagues appeared in American literature and were summarised by T. F. Allen and Hering [Proving—Allen], [Hering]. The proving shows burning along the oesophagus, constriction at the cardia with arrest of bolus (especially solids), bitter eructations, sallow cachectic facies, and characteristic fissures at mucocutaneous angles. Early clinical confirmations followed rapidly in gastric ulceration, oesophageal stricture, angular cheilitis, fissured nipples, and anal fissures [Clinical—Clarke], [Boericke].

  • Oesophagus & Cardia — Sensation as if food sticks at the cardia; burning, constriction, dysphagia (especially to solids); palliative sphere in oesophageal stricture and suspected malignant disease [Allen], [Hering], see Throat/Respiration/Stomach.
    Gastric Mucosa — Chronic gastric catarrh, ulcer tendency, bitter eructations, craving for cold drinks yet aggravation from hot; bitterness reflects its chemical bitter principle [Hughes], [Clarke], see Stomach.
    Mucocutaneous Junctions — Angular fissures (lips), rhagades of nipples and anus; dry, callous edges that crack and bleed on motion [Hering], [Allen], see Mouth/Rectum/Female/Skin.
    Skin & Ulceration — Indolent ulcers with hard margins; slow granulation; epithelial regeneration keynote [Clarke], [Boger], see Skin.
    Liver & Portal Area — Epigastric and right hypochondrial soreness in dyspeptic states; sallow, earthy complexion suggests hepatic sluggishness [Hughes], [Farrington], see Abdomen/Face.
    Rectum & Anus — Painful fissure, bleeding with stool, alternating constipation/diarrhoea in the cachectic; fissure edges dry and callous [Allen], [Boericke], see Rectum.
    Mammary/Nipple — Ragades in nursing women, fissured and intensely painful, often with burning; a frequent clinical sphere [Clarke], see Female.
    Respiratory Reflex Track — Tickling cough from oesophageal irritation; “oesophago-tracheal” reflex fits the vertical burning path [Hering], see Respiration/Chest.
    Circulation & Cachexia — Wasting, night sweats, and low mood in chronic ulcerative or malignant-adjacent states (palliative) [Hughes], [Kent], see Generalities/Perspiration.
    Mental Sphere of Illness — Fear of incurable disease, despair coloured by chronic burning pains and fissures; somatic-psychic loop typical of long dyspepsia and ulceration [Kent], [Tyler], see Mind.

Cold drinks (soothe burning track from fauces to epigastrium) [Clarke] — echoed under Throat/Stomach.
• Open air (head heaviness and mental oppression lift) [Hering] — see Head/Mind.
• Gentle walking after small meals (promotes gastric drainage, lessens cardial pressure) [Hughes] — see Stomach.
• Rest after eating (reduces epigastric burning and constriction) [Allen] — see Stomach.
• Mild local pressure over fissured parts (dulls raw pain temporarily) [Clinical—Clarke] — see Mouth/Rectum/Female/Skin.
• Morning hours (clearer head; less retrosternal burning) [Hering] — see Head/Throat.
• Plain, cool, non-irritating fare (lessens eructations and nausea) [Hughes] — see Food & Drink.
• Warmth to general body with cool sips for throat (mixed strategy that patients discover) [Clinical], see Generalities/Throat.
• Quiet company and reassurance (eases fear of fatal illness, lowers gastric spasm) [Kent] — see Mind/Stomach.
• Regular, small meals (prevents post-prandial arrest at cardia) [Allen] — see Stomach.
• Unguents/emollients locally (temporary ease of rhagades, yet recurrence points to constitutional need) [Clarke] — see Skin/Female.
• Gentle laxation without straining (prevents tearing pain of anal fissure) [Boericke] — see Rectum.

  • Swallowing solids (bolus arrests at cardia; intense retrosternal pain) [Allen] — mirrored in Throat/Stomach/Respiration.
    • Hot food or hot drinks (intensifies burning from fauces downwards) [Clarke] — cross-refer Stomach/Throat.
    • Night (restless from pain, fear of disease; sweats and burning) [Hering], see Sleep/Perspiration.
    • Cold, damp weather (fissures refuse to heal; edges crack anew) [Clinical—Clarke], see Skin/Rectum/Female.
    • Overeating or rich/fat food (bitter eructations, gastric weight, nausea) [Hughes], see Stomach/Food & Drink.
    • Emotional shock, anxiety about health (spasm at cardia worsens; “nothing will go down”) [Kent], see Mind/Throat.
    • Rapid temperature changes (skin/mucosa flare; fissures split) [Allen], see Skin/Mouth.
    • Pressure at epigastrium (exaggerates cardial soreness) [Hering], see Abdomen/Stomach.
    • Talking, laughing, opening mouth wide (angular cracks bleed) [Hering], see Mouth/Face.
    • First motion after rest (stiff, sore abdominal wall; fissures sting on rising) [Boger], see Generalities.
    • Spices, alcohol, very hot soups (gastric mucosa aflame; regurgitation) [Hughes], see Stomach.
    • Constipation and straining (tears the anal fissure; burning for hours) [Allen], see Rectum.
    • Dry, heated rooms (lips/nipples chap and crack; thirst yet aversion to hot liquids) [Clarke], see Mouth/Female/Food & Drink.
    • Late evening reading in bed (reflux and retrosternal burning prompt cough) [Hering], see Respiration/Sleep.

By Organ Affinity — Oesophagus/Stomach
Carbo animalis — Cancerous cachexia with glandular induration and burning; more putrid eructations and profound weakness; Condur. is more “cardial ring” and fissure-linked [Clarke], [Kent].
Hydrastis — Thick, ropy gastric catarrh with sinking at epigastrium; less of a temperature modality; Condur. has stronger worse-hot, better-cold and fissure keynote [Hughes], [Clarke].
Bismuthum — Burning pains, vomiting immediately after water; desires company; in Condur. vomiting is not cardinal and the oesophageal constriction dominates [Allen], [Kent].
Phosphorus — Burning, regurgitation, craves cold drinks but vomits when warm in stomach; more haemorrhagic tendency; Condur. has fissures and callous ulcers as anchors [Hering], [Clarke].
Kali bichromicum — Round, punched-out gastric ulcers with stringy mucus; Condur. shows fissure/epithelial borders and temperature modalities [Allen], [Boger].

By Fissures/Rhagades (Mucocutaneous)
Nitric acid — Splinter-like pains and bleeding fissures; offensive discharges; Condur. pains are burning/raw with callous edges and strong worse-hot/better-cold [Kent], [Allen].
Graphites — Cracks with honey-like oozing in corpulent, chilly subjects; Condur. fissures are drier, callous, with burning; strong oesophageal link [Clarke], [Boericke].
Causticum — Fissures with rawness and soreness, better warmth; Condur. is worse hot, better cold—opposite temperature profile [Kent].
Petroleum — Winter cracks, especially hands; more itching and eczema history; Condur. centres on angles of mouth, nipples, anus and oesophagus [Boger], [Clarke].
Pæonia — Painful anal fissures and ulcers with severe post-stool burning; Condur. adds epithelial callousness and systemic “burning track” [Allen], [Clarke].
Ratanhia — Knife-like anal pain hours after stool, relieved by hot applications; Condur. is worse hot and better cool—useful temperature discriminator [Kent].

By Modalities/Cachexia
Arsenicum album — Burning better heat; extreme restlessness and anguish; Condur. is burning worse hot, better cold; less restless but anxious about incurability [Kent], [Clarke].
Carbo vegetabilis — Great flatulence, desire to be fanned; lacks the fissure keynote and the marked cardial “ring”; Condur. more epithelial [Hughes].
Sulphur — Burning orifices and fissures with itching, unwashed look; Condur. burns without the Sulphur itch and leans to callous borders, fissured nipples/angles [Clarke], [Kent].

  • Complementary: Nitric acid — Splinter-pains and bleeding fissures complement Condur.’s callous rhagades; sequence often consolidates healing [Kent].
    Complementary: Graphites — Where oozing cracks predominate, Graph. may precede; Condur. consolidates epithelial repair [Clarke].
    Complementary: Pæonia & Ratanhia — Anal fissure pains (hot relieves for Ratanh.) may require temperature-guided alternation; Condur. completes epithelial healing [Kent], [Allen].
    Complementary: Hydrastis — Mucosal catarrh with sinking weakness; Hydr. prepares field; Condur. addresses fissure/stricture elements [Hughes].
    Follows well: Kali bichromicum — After punched-out gastric ulcer phase, Condur. steadies borders and burning track [Boger].
    Follows well: Carbo animalis — In malignant-adjacent cachexia when glands hard; Condur. palliates cardial constriction [Clarke].
    Follows well: Silicea — When indolent ulcers finally granulate, Condur. maintains epithelial integrity [Boger].
    Precedes well: Nux vomica — In irritable dyspeptics, Nux may clear hyperaesthesia before Condur.’s slower epithelial action [Kent].
    Antidotes (functional): Nux vomica — For medicinal gastric aggravations or over-irritation during dosing [Kent].
    Antidotes (emotional): Pulsatilla — For tearful anxiety with food aversions that hinder swallowing [Kent].
    Related/Compare: Causticum — Opposite thermal modality in fissures; use as comparator [Kent].
    Related/Compare: Phosphorus — Burning and cold drinks desire; haemorrhagic bent distinguishes Phos. [Clarke].

Condurango is an epithelial remedy with a syphilitic hue. Its essence is a triad: fissure, burning track, and constriction. The tissues it “chooses” are borders—angles and orifices where skin meets mucosa—and the inner “borderland” of the cardia where oesophagus meets stomach. There the patient feels as though life itself sticks: solids halt, swallowing is fearful, and a sting of flame travels downward. This track burns whenever heat is applied—hot soups, hot drinks, hot poultices—yet eases under the governance of coolness: cool sips, cool rinses, cool applications. This stark thermal polarity (worse hot, better cold) is not an afterthought but a constitutional polarity running through mouth, throat, stomach, nipples, anus, and ulcer margins [Clarke], [Allen], [Hering]. Psychologically, the patient lives in the shadow of incurability; the word “cancer” haunts, not always because pathology proves it, but because the felt sense of constriction and slow destruction conveys that story to the mind [Kent], [Tyler]. Miasmatically, the syphilitic current explains fissures that will not heal, ulcers that granulate slowly with callous edges, and cicatricial tendencies that narrow passages; a psoric dryness adds cracking, and a sycotic recurrence ensures the problem returns each winter or under the wrong indoor climate [Sankaran], [Boger], [Kent].
The kingdom signature (plant, Apocynaceae) brings bitters and reflexes—stimulation of mucosa that, in oversensitive subjects, becomes irritation. Thus, Condurango sits among gastric bitters (Hydrastis, Gentiana) yet is distinguished by its border fixation and temperature profile. Micro-comparisons clarify: Arsenicum burns but seeks heat; Condurango burns and seeks cold. Ratanhia’s anal agony loves heat; Condurango’s fissure hates it. Graphites weeps honey; Condurango is dry and callous. Kali bichromicum punches out ulcers; Condurango smooths and seals edges. Phosphorus craves ice but bleeds; Condurango craves coolness without marked haemorrhage [Clarke], [Allen], [Boger], [Kent].
Pace is slow. Reactivity is moderate: pains burn and smart rather than shoot violently; constriction is the key sensation. Thermal state is mixed: the body tolerates warmth, but the affected epithelium rejects heat; hence the successful “mixed” tactic of keeping the back warm while the oesophageal track receives cool sips—an observation patients teach us and which the materia confirms [Clinical—Clarke]. The core polarity is heat versus cool at the surface; constriction versus flow at the passage; despair versus reassurance in the mind. Treatment unfolds as steady consolidation: easing spasm so solids pass; encouraging fissures to knit; curbing the mind’s fear as the body’s borders soften. When the case displays this triad with the repeating temperature law across several orifices (lips and anus or nipples and throat), Condurango becomes a first-line consideration.

Condurango is invaluable for recurrent angular cheilitis, fissured nipples, and anal fissures that are dry, callous, and burn with heat but ease with cool applications; choose it especially when the same temperature law governs the oesophagus and stomach (worse hot drinks; better cold sips) [Clarke], [Allen]. In suspected oesophageal stricture or malignant-adjacent states it is palliative, reducing burning and spasm while aiding swallowing of soft solids (combine with diet and posture advice) [Hering], [Clarke]. Potencies: many classical authors employ tincture or low decimal/centesimal (Ø, 3X/6X) for local epithelial states, and 6C–30C constitutionally; higher (200C and above) have been used when the mental–modal pattern is clear and tissues are highly reactive [Boericke], [Kent]. Repetition: in acute fissure pain, low potencies can be given once to thrice daily until easing; in chronic epithelial repair, use infrequent doses (e.g., 30C weekly) and watch for steady granulation; avoid over-stimulation in the very irritable stomach [Kent], [Boger]. Adjuncts: cool rinses/sitz baths; emollients without heat; small, cool meals; avoid hot soups/drinks at night; gentle laxation to prevent straining—each adjunct mirrors the modality and speeds cure [Clarke], [Boericke].
Case pearls (one-liners):
• “Anal fissure worse hot, better cool irrigation; Condur. 30 closed a six-month wound after Ratanh. relieved pain only” [Clarke], [Kent].
• “Angular cheilitis splitting on laughter; worse heated rooms; Condur. 200 with humidity control prevented winter relapse” [Clinical—Clarke].
• “Cardial ‘ring’ with solids; cold milk sipped; Condur. 6X t.i.d. palliated enough to permit nutrition while work-up proceeded” [Hering].
• “Fissured nipples, stinging with hot compresses; cool rinses and Condur. 30 enabled continued nursing” [Clarke].

Mind
• Fear—disease, of being incurable. Keynote dread in cachexia; guides remedy choice when paired with burning track [Kent], [Tyler].
• Anxiety—health, about; worse at night. Night aggravation mirrors gastric burning and sweats [Hering].
• Hypochondriasis—dwells on symptoms. Sustained focus on swallowing and fissures [Kent].
• Despair—recovery, of. Syphilitic colouring of mind picture [Kent].
• Company—desires; better with reassurance. Calms spasm at meals [Kent].
• Fastidious about food temperature. Clinical hallmark—avoids hot, seeks cool [Clarke].
• Irritability from pain. Burning/fissure pains sour the temper [Hering].
Mouth
• Lips—cracks; angles of mouth. Angular cheilitis with callous edges; worse heat, better cool [Hering], [Clarke].
• Lips—fissures; bleeding on opening. Splits on talking/laughing; confirms modality [Allen].
• Mouth—burning; hot drinks aggravate. Thermal law central to case [Clarke].
• Stomatitis—aphthous; burning and raw. Epithelial signature [Clarke].
• Tongue—coated; bitter taste fasting. Gastric catarrh reflection [Hughes].
• Saliva—scanty by day, sticky at night. Nocturnal aggravation [Allen], [Hering].
Throat/Oesophagus
• Oesophagus—constriction at cardia; swallowing solids difficult. Pathognomonic sphere [Allen], [Hering].
• Oesophagus—burning; hot drinks aggravate. Confirms remedy law [Clarke].
• Swallowing—fear of choking; anticipatory spasm. Mind–body loop [Kent].
• Regurgitation—small amounts after hot food. Temperature-linked reflux [Hughes].
• Pain—retrosternal; radiating to back. Oesophageal referral [Allen].
• Better—cold drinks; sipped. Practical test in case [Clarke].
Stomach
• Eructations—bitter; after rich/hot foods. Bitter principle expression [Hughes].
• Pain—burning epigastrium; pressure aggravates. Matches epigastric tenderness [Hering].
• Appetite—variable; early satiety with spasm. Cardial “gate” symptom [Allen].
• Nausea—after hot soups. Thermal modality again [Clarke].
• Better—rest after eating; gentle walking. Post-prandial strategies [Allen], [Hughes].
• Vomiting—regurgitation of food/mucus. Secondary to spasm [Hering].
Rectum
• Fissure—anus; burning pain, bleeding. A chief clinical indication [Allen], [Clarke].
• Pain—after stool; hours. Knife-like, then burning [Allen].
• Constipation—alternating with diarrhœa. Debility pattern [Hughes].
• Straining—aggravates fissure. Avoid; confirm modality [Boericke].
• Better—cool applications/irrigation. Temperature law proves remedy [Clarke].
• Weather—cold damp aggravates healing. Seasonal relapse pattern [Clarke].
Skin
• Ulcers—indolent; callous edges. Slow granulation; epithelial sphere [Clarke], [Boger].
• Cracks—fingers; winter; heated rooms. Environmental modalities [Hering], [Clarke].
• Nipples—ragades; nursing. Stinging, burning; better cool [Clarke].
• Heat—local applications aggravate. Diagnostic for Condur. [Allen].
• Better—emollients (transient). Palliation signals constitutional need [Clarke].
• Weather—cold damp retards healing. Clinical management clue [Clarke].
Generalities
• Cancerous affections—epithelial; palliative sphere. Oesophagus/cardia focus [Clarke].
• Cachexia—night sweats; sallow face. Systemic tone [Hughes], [Kent].
• Food/drink—hot aggravates; cold ameliorates. Central modality [Clarke].
• Time—night aggravation. Nocturnal pattern across systems [Hering].
• Pressure—epigastrium aggravates. Exam finding [Hering].
• Motion—gentle after meals ameliorates. Practical advice [Hughes].
Sleep/Respiration (bridge rubrics)
• Cough—tickling; after hot drinks; night. Reflux-linked cough [Hering].
• Waking—2–3 a.m.; anxiety with burning. Nocturnal hallmark [Kent].
• Better—sitting up, cool sips. Postural/temperature relief [Clarke].
• Dreams—choking, narrow passages. Mind image of cardial ring [Tyler].
• Recumbency—aggravates retrosternal burning. Reflux physiology [Hering].
• Reading—evening aggravates cough. Lifestyle trigger [Hering].

Hering — The Guiding Symptoms of Our Materia Medica (1879): proving and clinical confirmations for oesophageal constriction, fissures, night aggravations.
Allen, T. F. — Encyclopædia of Pure Materia Medica (1874–79): compilation of American provings (Dowling et al.), gastric and oesophageal symptoms.
Clarke, J. H. — A Dictionary of Practical Materia Medica (1900): clinical cases of fissures, nipples, oesophageal stricture, temperature modalities; preparation notes.
Hughes, R. — A Cyclopædia of Drug Pathogenesy (1895): toxicology of bitter principles, gastric catarrh, historical non-homœopathic uses.
Boericke, W. — Pocket Manual of Homœopathic Materia Medica (1927): concise indications for fissures, epithelial ulcers; potency hints.
Kent, J. T. — Lectures on Homœopathic Materia Medica (1905): miasmatic lens, mental states in digestive remedies; comparisons (Ars., Graph.).
Boger, C. M. — Synoptic Key of the Materia Medica (1915): keynotes for ulcer, fissure, modalities; differential pointers (Kali bi., Ratanh.).
Farrington, E. A. — Clinical Materia Medica (1887): organ affinities—hepatic–gastric axis and cachexia remarks.
Nash, E. B. — Leaders in Homœopathic Therapeutics (1898): therapeutic emphasis on confirmatory clinical “leaders” (fissures, cachexia).
Dunham, C. — Homœopathy, the Science of Therapeutics (1879): observations on drug action in mucosa and constitutional indications.
Tyler, M. L. — Homœopathic Drug Pictures (1942): remedy portrait; dream imagery and psychological colouring in digestive remedies.
Boger, C. M. — Boenninghausen’s Characteristics & Repertory (1905): repertorial structure informing selected rubrics and relationships.

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