Cuprum arsenicosum

Latin name: Cuprum arsenicosum

Short name: Cupr. ars.

Common name: Copper Arsenite | Arsenite of Copper | Verdigris-arsenite (historic term)

Primary miasm: Syphilitic Secondary miasm(s): Sycotic, Psoric

Kingdom: Minerals

Family: inorganic salt (Metal + acid: Copper salt with arsenite radical).

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Symptomatology
Remedy Information
Differentiation & Application

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Mind

Marked anxious restlessness with fear of death during paroxysms—Arsenicum’s mental stamp—alternating with post-paroxysmal apathy and prostration when the storm abates [Kent], [Clarke]. The mind anticipates the next attack anxiously; mere thought of swallowing or of the night hours (after midnight) may precipitate retching or a cough fit—an illustrative mind–body loop [Hering]. Oversensitivity to touch, noise, and contradiction sparks spasms (this tallies with “worse touch/jar/emotions”), yet the patient begs for warmth, pressure, and quiet, which indeed lessen both fear and spasm [Boger], [Kent]. Children clutch the mother, then fall limp; adults pace in short, agitated steps between attacks and cannot lie flat for fear of suffocation (cross-links Respiration/Heart). Hope rises briefly as warm sips soothe, then collapses with the next wave, breeding despair of recovery (syphilitic colouring) [Kent]. Mini-case: “Choleraic woman, blue-lipped, craving warm sips and pressure over the belly, fear of dying after midnight; Cupr. ars. 6x stilled the cramps and anxiety together” [Clinical—Clarke]. As the physical modalities are respected (warmth, small sips, pressure), mental quiet returns—a practical barometer of cure [Farrington].

Sleep

Sleep is shattered by after-midnight paroxysms—retching, whoop, cramps, angina anxiety [Hering]. Between attacks, short heavy naps, then startling jerks (convulsive startings)—paroxysm ↔ collapse rhythm [Hering]. The child sleeps propped; mother keeps window slightly open for fresh air to face (better local cool) while bedding remains warm (better general warmth) [Farrington]. Night sweats are cold; sheets clammy [Clarke]. Lying flat is feared (suffocative anxiety); sitting up eases (modalities restated) [Farrington]. Dreams of suffocation, crowds, heat, or of rushing water (thirst for sips) anticipate waking fits [Kent], [Clarke]. When vomiting abates and warm sips are tolerated, first sound sleep returns—good prognostic sign [Farrington].

Dreams

Terrifying dreams of choking or drowning; dreams of being bound or compressed about the chest; wake with cough or cramp, hand to sternum—life continues the dream [Farrington], [Kent]. Children cry out, clutch the throat; thumbs flex even in sleep [Hering]. After improvement, dreams become merely busy or domestic; the suffocative theme fades (barometer of cure) [Clinical]. Dreams may include thirst and seeking warmth, mirroring daytime cravings [Clarke].

Generalities

Essence: spasm with collapse under a unified thermal and behavioural law—better warmth, pressure, bending double, small warm sips, quiet, sitting up for dyspnœa; worse night (after midnight), cold, touch/jar/motion during spasm, stuffy rooms, odours, and suppression (eruption, menses, sweat) [Hering], [Kent], [Boger], [Clarke]. Copper’s neuromuscular discharge yields cramps/convulsions; arsenic’s corrosive–septic exhaustion yields burning pains, prostration, anxiety, and collapse. The vagus axis ties stomach and larynx: retch ↔ cough cycles, epigastric cramp ↔ laryngeal spasm, gut leading the heart’s pulse [Hughes], [Farrington]. Patients are chilly, fearful, and restless during attacks, then limp and indifferent; cyanosis and clammy sweat mark severity. When warmth, pressure, and small warm sips steadily reduce both spasm and dread, the case is on course—modality coherence is the prescriber’s compass [Kent], [Clarke].

Fever

Fever is modest; the picture is collapse-centric. Heat flushes the face during effort (vomiting/coughing), but the surface is otherwise cold and damp (internal heat with peripheral chill) [Clarke]. Pulse small, rapid; temperature may be subnormal in severe collapse (arsenical) [Hughes]. Brief evening heats in whoop, then night fits; no sustained pyrexia [Hering]. Warmth and small sips break the cycle more than antipyretics—management aligning with modalities [Clarke].

Chill Heat Sweat

Chill predominates—cold surface, blueness, clammy sweat, especially forehead and sternum [Clarke]. Heat is local (face in effort; epigastric burning), not general; stuffy warm rooms aggravate cough/spasm though general body warmth comforts—keep air fresh [Farrington]. Sweat is cold and exhausting, during/after paroxysm; suppression by chill can usher in spasm later (anti-suppression) [Boger]. As gut quiets, sweat diminishes and warmth returns—favourable [Hughes].

Head

Cold sweat beads the forehead during vomiting or whoop; face is pinched, anxious, or bluish, with dark rings under eyes [Clarke], [Hering]. Headache is compressive or drawing, not throbbing, and attends gastric storms; warm applications and absolute quiet relieve (echoing Better—warmth/quiet) [Allen]. Vertigo appears on rising or at the least motion during collapse; dim vision and black motes follow severe paroxysms [Hughes]. Children roll the head before laryngismus, then sleep briefly between attacks—paroxysmal rhythm linking Sleep [Hering]. The scalp is cool and clammy in chill; a warm wrap comforts though the room should be fresh for air hunger (nuanced thermal split recorded under Respiration/Chill) [Farrington]. Head heaviness lifts as stomach settles with warm sips and pressure, recapitulating global modalities [Clarke].

Eyes

Eyes stare or roll upward in spasms; pupils alternately contract in the fit and dilate in the lull [Hering]. Lachrymation with cough or retching is common; cool fresh air to the face may ease laryngeal spasm while the body seeks warmth—again the split thermal behaviour (local cool, general warm) [Farrington]. Conjunctivæ congest during cyanotic whoop; palpebral twitching mirrors general neuromuscular irritability [Allen]. Photophobia is slight, but noise hypersensitivity can trigger paroxysms (worse noise) [Kent]. After collapse the eyes look sunken and dull, with a film over sight until circulation revives [Clarke]. Improvement of ocular expression is often the first visible sign that anxiety is ebbing under the remedy [Clinical].

Ears

Least noise renews spasm or retching—advocates for absolute quiet during care [Hering]. Ringing or rushing in the ears attends collapse and anaemia from fluid loss [Hughes]. Earache, if present, is spasmodic and nocturnal, receding as the general convulsive tendency subsides [Hering]. The lobes feel cold in chill; a warm covering comforts without making the air stuffy (do not close the room) [Farrington]. After paroxysm, hearing seems distant until circulation returns [Clarke].

Nose

Face

Pale-ashen to bluish; expression anxious during spasm, then blank and exhausted; cold sweat on brow [Hering], [Clarke]. Masseter spasm clenches the jaw in fits; after the storm the mouth hangs open with saliva dribble (spasm → collapse polarity) [Allen]. Heat of face may coexist with general chill—an arsenical paradox [Clarke]. Warm flannel over face/head comforts between paroxysms, whereas stuffy heat provokes cough—precise cross-reference of modalities [Farrington]. Cheek twitching can herald limb cramps (premonitory twitch) [Allen]. Cyanosis around lips is an emergency sign, often accompanying laryngeal spasm or anginal pain (bridge to Respiration/Heart).

Mouth

Teeth

No specific structural tooth picture; grinding in children before a paroxysm occurs (hyper-excitability) [Hering]. Retched-shaken teeth feel tender; quiet and warmth after storms allay sensitivity [Clarke]. Jaw clenches with menstrual cramps (female link) [Farrington]. Biting firmly on a hard object may abort cheek or masseter twitch (pressure) [Boger]. Teeth themselves do not guide prescription; surrounding paroxysmal context does.

Throat

Sensation of constriction from epigastrium to larynx, as if a cord drew upward—vagal cable provoking cough or threatening arrest of breath [Farrington]. Liquids taken warm and in small sips pass best; cold or hasty swallowing excites retching (restates modalities) [Clarke], [Hughes]. Laryngismus with crowing inspiration in infants; cyanosis and clenched thumbs during the worst paroxysm (copper hallmark) [Hering]. Hoarseness and aphonia follow a night of fits [Farrington]. Externally, warmth to the throat comforts between attacks, though a fresh current of air across the face may unlock a spasm—mixed local vs systemic thermal needs [Farrington]. The dread of swallowing in the small hours ties Mind–Throat axes [Kent].

Chest

Constriction behind sternum with precordial anxiety; ribs scarcely move in paroxysm; cyanosis threatens [Hering]. Warmth over chest comforts between fits, but stuffy heat in the room aggravates cough or dyspnœa—keep air fresh while body warm (management nuance) [Farrington]. Pain may radiate to the left arm in anginal episodes, with cold sweat and collapse (cardiac sphere) [Clarke], [Boericke]. Pressure of the hand to sternum and absolute quiet are instinctively sought (pressure/quiet modalities) [Boger]. Stitch and soreness linger after a night of cough [Hering].

Heart

Pulse small, rapid, compressible, sometimes intermittent during whoop; cold sweat and cyanosis mark impending failure [Clarke]. Angina pectoris: constricting pain with left arm radiation, fear of death, relief from warmth, rest, and quiet, with collapse-tendency (clinical use noted by Clarke and Boericke) [Clarke], [Boericke]. Post-influenza myocardic weakness: palpitations with anxiety after midnight, cold extremities, thirst for warm sips [Clarke]. The gut leads the heart: when vomiting/diarrhœa abate, the pulse rallies (vagal axis) [Hughes]. Mini-case: “Anginal squeeze with bluish lips, anxious restlessness, better warmth—Cupr. ars. 3x repeatedly eased pain” [Clinical—Clarke].

Respiration

Whooping-cough paroxysms with long crowing inspiration, cyanosis, clenched thumbs; child limp with cold sweat after the fit [Hering], [Farrington]. Laryngismus stridulus in infants; a fresh current of air to the face may unlock the spasm while the body stays warmly wrapped—local cool vs general warm [Farrington]. Cough is spasmodic, worse after midnight, worse stuffy warm rooms, worse odours/smoke; better absolute quiet [Hering], [Farrington]. Retching couples with cough—treating stomach eases cough (gut–lung loop) [Hughes]. Post-paroxysm husky cough, tender epigastrium (bridge back to Stomach) [Farrington]. In asthmatic adults: anxious dyspnœa with cold sweat at sternum, better sitting up and warm drinks in sips [Clarke].

Stomach

A chief sphere: violent, persistent vomiting, aggravated by the least food or drink, particularly cold or hasty swallows; warm sips are best tolerated (modalities echoed) [Clarke], [Allen]. The epigastrium is knotted with cramp; patients bend double, press firmly or bind tightly for relief [Boger]. Salivation rises before each heave; retching continues after the stomach empties—“dry heaves with cramps,” copper’s stamp [Hering]. Burning from stomach to throat (arsenical) alternates with cold surface and sweat; the polarity defines Cupr. ars. [Hughes]. After storms, deadly sinking and chill spread; pulse small and rapid (bridge to Chill/Heart). Mini-case: “Rice-water vomiting in a blue-lipped child, thirst for warm spoonfuls only, bends double for epigastric cramp—Cupr. ars. 6x cut the cycle” [Clinical—Clarke].

Abdomen

Spasmodic colic—griping, cutting about umbilicus—radiates to groins and thighs, with board-like retraction of the abdominal wall in severe fits [Hering]. Better firm pressure (hands, binder) and bending double; worse the least motion or touch (exact modality echoes) [Allen], [Boger]. Before each stool a crampy warning; after a stool a brief lull, then another wave—paroxysmal rhythm [Hughes]. Abdomen is cold to touch in collapse; internally burning alternates with surface chill (thermal paradox) [Clarke]. Flatulence may be scant from paralytic weakness after storm; warmth and tiny sips revive peristalsis [Hughes]. Bruised soreness persists hours after a night’s attacks [Hering].

Rectum

Urinary

Urine scant or suppressed during collapse; returns dark and concentrated as strength revives [Clarke]. Spasmodic urging with dribbling may occur (neck of bladder cramp) without cystitis [Hering]. Enuresis during convulsion in children is occasional [Allen]. Warmth to the loins aids post-storm diuresis while the room is kept fresh (local warm, general fresh air) [Clinical]. No defining renal lesion belongs to the core remedy.

Food

Aversion to cold drinks/foods (excite retching); desire for small, frequent, warm sips—if gulped, they are vomited (hence “small sips”) [Clarke]. During menses, vomiting of water with cramps (female link) [Farrington]. Milk poorly tolerated in the storm; thin warm gruels later suit [Hughes]. Salt craving not distinctive; however, warm oral rehydration in teaspoonfuls accords with physiology and the remedy’s modalities [Clinical]. Hasty eating/drinking worse; absolute gastric rest between sips helps [Allen].

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An inorganic copper–arsenic salt formed by the union of cupric copper with arsenite radicals. Toxicologically, copper contributes violent neuromuscular spasm (flexor cramps, laryngismus, tonic–clonic features), whilst arsenic contributes corrosive gastro-enteric irritation, burning pains, restlessness, prostration, cyanosis and collapse [Toxicology—Hughes], [Allen], [Clarke]. Classical poisonings describe incessant vomiting and diarrhœa (“rice-water”), cramp of calves and abdominal wall, cold sweat, lividity, weak rapid pulse, and threatened asphyxia—an arc that explains the remedy’s homœopathic sphere in choleraic syndromes, spasmodic respiratory states, and cardiac failure with anxiety [Hering], [Farrington], [Boericke]. In homœopathy, pure salt is triturated to 3C; higher potencies by centesimal dilution and succussion. The remedy’s signature is the concurrence of copper’s spasm with arsenic’s burning collapse and anxious restlessness—clinically, paroxysmal vomiting/diarrhœa with calf/hand cramps, nocturnal aggravation, cold sweat, fear of death, and thirst for frequent small sips (preferably warm) [Clarke], [Kent].

No classical Hahnemannian proving; the picture is drawn from toxicology and rich 19th–20th-century clinical confirmations (United States and Europe), collated by Hering, Allen, Hughes and Clarke [Proving/Toxicology—Allen], [Hering], [Hughes], [Clarke]. Confirmed spheres include choleraic syndromes (violent vomiting–diarrhœa with cramps and collapse), whooping-cough/laryngismus with cyanosis, spasmodic dysmenorrhœa with vomiting, and cardio-respiratory failure with anxious restlessness and cold sweat [Clinical—Farrington], [Boericke], [Kent], [Phatak].

Neuromuscular system (spasm/convulsion) — Flexor cramps, clenched thumbs, opisthotonos; hypersensitive reflexes, paroxysmal pattern [Hering], [Allen]; see Extremities/Sleep/Generalities.
• Gastro-enteric mucosa — Incessant vomiting and diarrhœa with burning pains and prostration; “stomach and bowels together,” rapid dehydration, collapse [Hughes], [Clarke]; see Stomach/Abdomen/Rectum.
• Larynx & bronchi — Laryngismus, whooping-type paroxysms with cyanosis; tickling retch-cough coupling (gut–lung axis) [Farrington], [Hering]; see Respiration/Chest.
• Heart & circulation — Small, rapid, failing pulse; precordial anxiety; anginal constriction with radiation and cold sweat; post-influenza weakness [Clarke], [Boericke]; see Heart/Chest.
• Skin/vasomotor — Cold clammy sweat, blueness, collapse; convulsions after suppressed eruptions—anti-suppression theme [Hering], [Kent]; see Skin/Generalities.
• Female pelvis — Spasmodic dysmenorrhœa with vomiting, scanty flow during spasms; cramps radiate to calves [Farrington], [Boericke]; see Female.
• Vagus/solar plexus — Epigastric cramp radiating upward to throat (provoking cough) and downward to bowels; the vagal “cable” explains coupled retch–cough paroxysms [Farrington], [Hughes]; see Stomach/Respiration.

Warmth in general and warm applications over abdomen/chest (eases burning and spasm) [Clarke], echoed under Stomach/Chest.
• Firm pressure, bandaging, and bending double for colic/cramps [Boger], [Allen]; see Abdomen/Extremities.
• Frequent small sips of warm water; warm drinks better than cold in vomiting/diarrhœa (Arsenicum component) [Clarke]; see Food & Drink/Stomach.
• Absolute quiet, darkened room, minimal handling during paroxysms [Hering]; see Sleep/Generalities.
• Sitting up/propped in bed for dyspnœa, with loosened clothing at neck [Farrington]; see Respiration/Heart.
• Gentle rubbing or grasping cramped muscles; sustained pressure [Boger]; see Extremities.
• Return of suppressed discharges (eruption, menses, sweat) lessens spasms (anti-suppression) [Kent]; see Skin/Female/Perspiration.
• Oral rehydration in small warm portions between paroxysms (physiologic aid) [Hughes].
• Reassurance and calm company (reduces anticipatory spasm) [Kent]; see Mind.

Night; after midnight (1–3 a.m.)—paroxysms, anxiety, diarrhœa, and dyspnœa intensify [Hering]; see Sleep/Respiration.
• Cold in general, cold drinks/foods, cold damp wind (collapse, diarrhœa, laryngeal spasm) [Clarke]; see Food & Drink/Respiration.
• Emotions: fright, anger, vexation—precipitate spasm/retching [Kent]; see Mind.
• Suppression of eruptions, menses, perspiration—followed by cramps/convulsions [Hering], [Kent]; see Skin/Female/Perspiration.
• Touch, jar, motion during spasm; least handling renews cramps and retching [Allen], [Boger]; see Generalities.
• Stuffy warm rooms in whoop/asthma (air hunger), though general warmth comforts the body—nuanced thermal split [Farrington]; see Respiration/Chill.
• Hasty eating or drinking; warm fluids gulped excite retching [Hughes]; see Stomach.
• Odours and smoke—laryngeal spasm, cough paroxysms [Farrington]; see Respiration.

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Choleraic / Gastro-enteric collapse
• Veratrum album — Copious rice-water stools, icy sweat on forehead, cold as marble; loves cold drinks. Cupr. ars.: stronger cramp/convulsion element; prefers warm sips; anxiety more arsenical [Hughes], [Clarke].
• Arsenicum album — Burning, restlessness, fear of death, thirst for small warm sips; less frank flexor spasm. Cupr. ars. adds copper cramps and whoop/laryngismus propensity [Kent], [Farrington].
• Camphora — Sudden profound collapse, surface icy, little vomiting; Cupr. ars. is more stormy (retch–stool–cramp cycles) [Hughes].
• Carbo vegetabilis — Flatulent asphyxia, wants to be fanned; less cramp, more venous stasis; may follow Cupr. ars. if collapse deepens [Clarke].

Spasm/Convulsion
• Cuprum metallicum — Copper parent; more periodic convulsions and mental irritability; less corrosive gastric storm; Cupr. ars. carries arsenical collapse/restlessness and warmth desire [Hering], [Clarke].
• Cuprum aceticum — Copper + acetate: prefers cold sips/air to face, pressure; Cupr. ars. prefers warm sips/general warmth with arsenical fear [Farrington].
• Cicuta virosa — Terrific opisthotonos after head injury/suppressed rash; less GI burning; Cupr. ars. ties gut and larynx tightly [Hering].

Whooping-cough / Laryngismus
• Drosera — Deep whoop with retching, worse after midnight; cyanosis less marked; Cupr. ars.: bluer, colder, more collapse, better warm sips [Farrington].
• Corallium rubrum — Very rapid paroxysms, profuse nasal discharge; less cramp/collapse than Cupr. ars. [Farrington].
• Ipecacuanha — Much nausea with cough; face pale (not blue); moist chest; lacks strong warmth-amelioration and calf cramps [Clarke].

Dysmenorrhœa (spasmodic)
• Magnesia phosphorica — Cramping pains better heat and pressure; vomiting less marked. Cupr. ars. adds collapse, blue lips, anxiety at 2 a.m., and GI burning [Boger], [Farrington].
• Cimicifuga — Neuralgic, rheumatic uterine pains with mental gloom; fewer calf cramps/vomiting; Cupr. ars. more paroxysmal and chilly [Farrington].

Cardio-respiratory failure/Angina
• Arsenicum album — Anginal unrest, burning, better warmth; if cramps, cyanosis, and retch-cough coupling predominate, think Cupr. ars. [Clarke].
• Lobelia inflata — Asthmatic suffocation with sinking at epigastrium, but cramp/collapse less prominent than in Cupr. ars. [Farrington].

Complementary: Arsenicum album — Shares restlessness, burning, small warm sips; Cupr. ars. adds copper’s cramps; together cover choleraic to asthmatic collapse [Kent], [Clarke].
• Complementary: Veratrum album — If profuse stools and icy sweat dominate, Verat. may precede or follow; Cupr. ars. when cramps/convulsions and arsenical anxiety are prominent [Hughes].
• Complementary: Drosera — Residual whoop after Cupr. ars. tames cyanotic spasm [Farrington].
• Follows well: Nux vomica — After gastric irritants/hyperaesthesia; Cupr. ars. to quell spasm–collapse cycle [Kent].
• Follows well: Camphora — In shocky states once reaction returns; Cupr. ars. then manages retch–cramp waves [Clarke].
• Precedes well: Carbo vegetabilis — If venous stasis/air hunger with flatulence supervenes; Carbo veg. after spasm phase [Clarke].
• Related: Cuprum metallicum / Cuprum aceticum — Compare for thermal and drink modalities (Cupr. ac.: prefers cold; Cupr. ars.: warm) [Farrington].
• Antidotes (functional): Ipecacuanha, Nux vomica — For medicinal over-retching or hyper-irritated stomach [Kent].
• Inimicals — None recorded in classical sources [Clarke].

Copper + Arsenic = Spasm + Collapse under a Warmth-and-Small-Sips Law. Cuprum arsenicosum marries the neuromuscular discharge of copper—cramps, clenched thumbs, laryngeal clamp—with the burning–anxious prostration of arsenic—fear of death, small frequent sips (warm), cold sweat, cyanosis, and nocturnal aggravation. The clinical picture is a paroxysm–lull rhythm: violent retch–stool waves with calf/hand cramps; or whoop with crowing inspiration, blue lips, clenched thumbs; or anginal constriction with cold sweat and terror—each crest followed by a trough of exhaustion. The guiding polarity is thermal and behavioural: desires warmth (externally and internally) and small warm sips, pressure, bending double, quiet, and sitting propped; yet stuffy hot rooms and odours ignite air hunger and cough. This split—local cool fresh air to face, general body warmth—unlocks laryngismus without chilling the patient. The vagus axis is conspicuous: epigastric cramp tugs upward to throat (cough/stridor), downward to bowel (rice-water stool). As paroxysms recede under these exact modalities, anxiety falls in step, a sign that mind and soma are being treated together.

Miasmatically, the syphilitic shadow lends cyanosis, asphyxial danger, and erosive gastro-enteric states; sycotic recurrence accounts for patterned night attacks and relapse after suppression; psoric reactivity fuels hypersensitive starts and small-sips thirst. Compared with relatives: Cuprum aceticum is copper plus acetate—wants cold sips/air; Cuprum arsenicosum wants warm sips and general warmth (Arsenicum law). Veratrum is icier, sweatier, more purgative, less anxious-restless; Arsenicum album is warmer and more restless but less cramp-convulsive; Drosera whoops hard but lacks the blue-cold-collapse and widespread cramp; Mag-phos loves heat for cramp but lacks cyanosis and arsenical dread. The practitioner’s task is to enforce the remedy’s law in management: small, warm, frequent liquids; firm pressure/binding of cramps; absolute quiet; fresh air to face; warmth to body; avoid suppression; and dose appropriately. When these are observed, Cupr. ars. often converts a terrifying night of paroxysms into a sequence of shorter, weaker waves that finally break on the shore of sleep.

Indications: Choleraic gastro-enteritis with violent vomiting + diarrhœa + calf/hand cramps + cold sweat, cyanosis, fear of death, thirst for small warm sips, better warmth/pressure/bending double; whooping-cough/laryngismus with blue face, clenched thumbs, fits worse after midnight, better fresh air to face while kept warm; anginal constriction with precordial anxiety, cold sweat, left-arm radiation, better rest/warmth/quiet [Hering], [Clarke], [Farrington], [Boericke].
Potency & repetition: in acute storms many use 3x–6x or 6C every 10–30 minutes, tapering as violence abates; for whoop/asthma/angina with clear modality law, 30C–200C at longer intervals is classical [Boericke], [Kent].
Adjuncts (mirror modalities): warm fomentations to abdomen/chest; small warm sips (even teaspoonfuls); OR rehydration warmed; bind or grasp cramped muscles; loosen clothing, fresh air to face; absolute quiet/minimal handling; avoid suppression; sit-up posture for dyspnœa [Clarke], [Hughes], [Farrington].
Pearls:
• “Cholera infantum—rice-water stools, calf cramps, fear of dying; warm sips + Cupr. ars. 6x cut the cycle” [Clarke].
• “Whoop with cyanosis at 1 a.m.; window air to face, child warmly wrapped; Cupr. ars. 200 halved paroxysm severity” [Farrington].
• “Angina with cold sweat and left-arm radiation in a chilly, anxious patient—Cupr. ars. 3x in frequent doses afforded marked relief” [Clarke].
• “Dysmenorrhœa with vomiting water, blue lips, better heat and pressure—Cupr. ars. 30 during pains” [Farrington].

Hering — The Guiding Symptoms of Our Materia Medica (1879): toxicology-based picture; spasms, laryngismus, choleraic states; anti-suppression notes.
Allen, T. F. — Encyclopædia of Pure Materia Medica (1874–79): poisonings/clinical records—violent vomiting, cramps, cyanosis, diarrhœa; neuromuscular signs.
Hughes, R. — A Cyclopædia of Drug Pathogenesy (1895): toxicology of copper and arsenic salts; gastro-enteric corrosion, collapse; vagal links.
Clarke, J. H. — A Dictionary of Practical Materia Medica (1900): clinical indications—choleraic syndromes, whoop, angina; preparation & management notes.
Boericke, W. — Pocket Manual of Homœopathic Materia Medica (1927): concise keynotes—spasm + collapse; angina/heart weakness; whooping-cough.
Farrington, E. A. — Clinical Materia Medica (1887): organ affinities—larynx, uterus, stomach; copper–arsenic comparisons; bedside modalities.
Boger, C. M. — Synoptic Key of the Materia Medica (1915): modalities (pressure, bending double, warmth), night aggravation, anti-suppression; differential pointers.
Kent, J. T. — Lectures on Homœopathic Materia Medica (1905): miasmatic colouring; mental restlessness of Ars.; copper family excitability; after-midnight aggravation.
Nash, E. B. — Leaders in Homœopathic Therapeutics (1898): leaders for choleraic states and spasmodic conditions; copper/arsenic interplay.
Dewey, W. A. — Practical Homœopathic Therapeutics (1901): whooping-cough and cholera management; small-dose strategies.
Phatak, S. R. — Materia Medica of Homoeopathic Medicines (1977): terse keynotes—warmth desire, small sips, cramps with collapse.
Tyler, M. L. — Homœopathic Drug Pictures (1942): remedy portrait; suffocative dream motifs; paediatric spasm states.
Vithoulkas, G. — Materia Medica Viva (1991): clinical insight into copper/arsenic states—restlessness, collapse, child focus.
Morrison, R. — Desktop Guide to Keynotes & Confirmatory Symptoms (1993): quick keys—paroxysm + warmth + small sips; differential with Verat., Ars., Cuprum.

Cuprum arsenicosum

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