• Uterus & ovaries — delayed/suppressed menses, dysmenorrhoea, menorrhagia; threatened miscarriage; pelvic congestion with bearing-down [Hale], [Clarke], [Boericke].
• Bladder & urethra — irritative frequency, smarting, pre-menstrual vesical urging; neck of bladder sensitive [Clarke], [Allen].
• Lumbosacral region — dull sacral ache radiating to groins and thighs, worst before or during menses [Hering], [Boger].
• Respiratory mucosa — cough, hoarseness, or even haemoptysis as “vicarious menstruation” when the period is suppressed or delayed [Clarke], [Hale].
• General nutrition — anaemic, easily tired adolescent girls; chlorotic tendencies with pallor and cold extremities [Clarke], [Boericke].
• Rectum — pelvic congestion with haemorrhoidal fullness around menses [Hering].
• Mammae — premenstrual fulness and aching with pelvic-vesical irritability [Clarke].
• Mind — anxiety and fretfulness around expected menses; hypersensitivity from sleep loss due to urinary frequency [Clarke], [Kent].

• When menses begin to flow (relieves pelvic/vesical congestion) [Clarke].
• Warmth and hot applications across pelvis or sacrum [Boericke].
• Gentle walking after first onset of flow (promotes decongestion) [Hale].
• Frequent small voidings (momentary ease of vesical pressure) [Allen].
• Rest, recumbent posture with knees slightly flexed [Boger].
• Open air, cool room for menstrual headache/crowded feeling [Clarke].
• Bland diet, avoidance of stimulants that irritate bladder [Hughes].
• After stool, when pelvic pressure is shared/relieved [Hering].

• Before menses; if the period is delayed or suppressed [Clarke], [Hale].
• Sudden chill, damp weather; getting feet wet (pelvic/vesical catarrh) [Hughes], [Clarke].
• Exertion, long standing or sitting on a hard seat (pelvic drag) [Boger].
• Coition during congestive times (vesical/uterine irritability) [Clarke].
• At night—must rise to pass water; sleep broken [Allen], [Clarke].
• Coffee, alcohol, spices—increase vesical burning/frequency [Hughes].
• Mental excitement or fright—brings on urging or suppresses the flow [Clarke].
• Left lateral decubitus (some writers note more pelvic pressure on left) [Clinical—Clarke].

Fretful, anxious anticipation before the period; easily moved to tears; worries about “being late” and fears flooding when it does come [Clarke]. Restless from frequent night calls to urine; irritable by morning; concentration poor, with a “crowded” head that clears when the menses set in—echoing the Better-for-flow modality [Clarke], [Hale]. Oversensitive to contradiction around menses; nervous palpitation on lying down from pelvic unrest [Kent], [Clarke]. Less despondent and inert than Sepia, but shares the pelvic-bearing-down and urinary frequency; Senecio is softer, more chlorotic and pre-menstrual in tone [Clarke], [Kent]. [Clinical]

Dull frontal heaviness with a sense of distension, worse before the flow, better when it starts [Clarke]. Vertex and occiput ache with sacral drag; giddiness on rising during suppressed or delayed menses [Hale], [Hering]. Headache alternates with urinary urging; open air and gentle motion help; close warm rooms aggravate—links to general modalities [Clarke]. Compared with Puls. (changeable, tearful, better open air), Senecio has stronger vesical association and sacral pain before menses [Clarke], [Farrington]. [Clinical]

Pale lids in chlorotic girls; dimness on rising during delayed menses; ocular congestion is secondary and functional [Clarke]. [Clinical]

Noises in ears with anaemic states before menses; morning humming with pallor; better after breakfast and on walking slowly [Clarke]. [Clinical]

Coryzoid sensitivity to chilling when the period is late; some report nosebleed as vicarious discharge, less frequent than chest bleeding [Clarke], [Hughes]. [Clinical]

Pale, cool; bluish circles under eyes; flushes at trifles premenstrually; returns to normal colouring once flow is established [Clarke]. [Clinical]

Sticky morning mouth from bad night; small thirstless sips; tongue pale with indentations in anaemic subjects [Clarke]. [Clinical]

Gnashing from pelvic discomfort at night is occasionally noted; odontalgia is not a keynote [Hering]. [Clinical]

Sensation of dryness with frequent need to swallow; hawks slightly tenacious mucus before menses when catarrh is increased by chill [Hughes], [Clarke]. [Clinical]

Nausea before menses; aversion to rich foods; faint, empty sinking relieved by warm drinks [Clarke], [Hale]. Appetite capricious; easily dyspeptic if chilled during the “due time,” which then suppresses the flow and awakens vesical irritability [Hughes], [Clarke]. [Clinical]

Pelvic weight with bearing-down, worse standing/walking fast; better warmth and when the flow becomes free [Clarke], [Boericke]. Griping to groins, with a need to pass water often; flatulent distension and a sense that the bladder and rectum are crowded [Hering], [Boger]. [Clinical]

Frequent urging, especially at night and before menses; scanty, smarting urine with sensitivity of the neck of bladder [Clarke], [Allen]. Each draught of cold air or chill of the feet increases urging; warmth soothes. In some cases, vesical irritation is the earliest sign that the period is delayed; once the flow starts, urging abates (cross-reference Better-for-flow) [Clarke], [Hale]. Compare Staph. (honeymoon cystitis), Chimaph. (must strain; scalding), Puls. (mild catarrh with changeable mood); Senecio is recognised by its pre-menstrual vesical pattern and sacral drag [Clarke], [Farrington]. [Clinical]

Fullness and haemorrhoidal protrusion in the pre-menstrual week; urging to stool with little relief of pelvic weight; better after a soft stool with warmth to sacrum [Hering], [Clarke]. [Clinical]

Less important; irritative bladder with sacral aching in young men after chill; occasional urethral smarting; not a sexual weakness remedy per se [Clarke]. [Clinical]

Key sphere. Amenorrhoea or delayed menses with pelvic weight, vesical frequency, sacral soreness, and mental fretfulness [Clarke], [Hale]. Dysmenorrhoea with dragging to thighs; better when a bright red flow establishes; if suppressed by chill/emotion, there may follow cough, hoarseness, or haemoptysis—a “vicarious” outlet [Clarke]. Menorrhagia in pale, easily tired women; bleeding aggravated by exertion; flow may be too early and too profuse with urinary urging and backache [Boericke], [Clarke]. Threatened miscarriage at early months with vesical irritability and aching sacrum—rest, warmth, and Senecio have clinical note here [Hale], [Clarke]. Leucorrhoea, yellowish or bland, worse before menses, with bladder sensitivity [Hering], [Clarke]. Compared with Sep. (bearing-down with indifference) and Caul. (spasmodic uterine pains), Senecio is the vesical-uterine nexus centred on the pre-menstrual window [Farrington], [Boericke]. [Clinical]

Short breath on exertion premenstrually; sighing; oppression in close rooms; better outdoors [Clarke]. [Clinical]

Palpitation before menses in anaemic girls, evening worse; calms after flow or in open air [Clarke]. [Clinical]

Hoarseness and teasing cough when menses are checked or delayed; may go on to spitting of blood (vicarious menstruation); chest tightness better as uterine flow is restored, which exemplifies the remedy’s polarity [Clarke], [Hale]. This differentiates from Bry. (suppressed menses with pleuritic stitch and dry cough) and from Puls. (mild catarrh, weepy mood), giving Senecio a more vesical-uterine trigger [Farrington]. [Clinical]

Dull sacral ache, dragging to loins and inner thighs, worst before or during menses; must support back with hands when standing; relieved by warmth and as flow becomes freer [Hering], [Boger], [Clarke]. [Clinical]

Weak, trembling legs during suppressions; cold hands/feet in chlorotic girls; cramps in calves before menses [Clarke]. [Clinical]

Pale, cool; chilblain tendency when menses are delayed (psoric sensitivity to cold and damp) [Hughes]. [Clinical]

Broken by urinary urging before the period; cannot find a comfortable position for the sacral ache; drowsy by day, wakeful by early morning hours from pelvic pressure [Allen], [Clarke]. Dreams anxious, of appointments missed, reflecting pre-menstrual worry [Clarke]. [Clinical]

Dreams of being late, of blood, or of searching for a lavatory; relieved after a night start and passing urine—mirrors daytime polarities [Clarke]. [Clinical]

Little fever; alternating chills and flushes in pre-menstrual week; heat in face with cold hands [Clarke]. [Clinical]

Chilliness on slight exposure; heat of head and face before menses; perspiration easy on least exertion in anaemic states [Clarke], [Hughes]. [Clinical]

Aversion to rich/fatty food before menses; desires warm drinks; aggravation from coffee/alcohol (vesical) [Hughes], [Clarke]. [Clinical]

The portrait is of a young or climacteric woman with pre-menstrual pelvic congestion, irritable bladder, and sacral dragging, whose general state is anaemic and chilly. The keynote polarity—worse before/when suppressed, better when the flow appears—threads Mind, Head, Chest, Back, and Urinary sections, making a coherent totality. Where suppression provokes vicarious respiratory symptoms, the Senecio choice is sharpened [Clarke], [Hale], [Boericke]. [Clinical]

• Pulsatilla — Delayed/suppressed menses with changeable mood; better open air; less vesical irritability than Senec.; more chilliness of feet; bland discharges [Clarke], [Farrington].
• Sepia — Bearing-down “as if everything would protrude,” indifference/irritability; urinary frequency present but with ptosis/relaxation; not specifically pre-menstrual vesical; darker temperament [Kent], [Clarke].
• Caulophyllum — Spasmodic, neuralgic uterine pains; erratic flow; useful in dysmenorrhoea but lacks vesical neck sensitivity of Senec. [Farrington], [Boericke].
• Cimicifuga (Actea-rac.) — Nervous, rheumatic dysmenorrhoea with mental gloom; back/neck aching; less vesical keynote; more neuralgic [Farrington], [Clarke].
• Trillium — Menorrhagia with sacral-to-hips pains and faintness; flooding on least motion; no pre-menstrual urinary pattern [Clarke], [Boericke].
• Viburnum-op. — Cramping dysmenorrhoea with threatened abortion; cramps extend to thighs; less bladder focus [Boericke].
• Sabina — Bright red menorrhagia with pains shooting from sacrum to pubes; tendency to clots; sexual organ hyperaemia; more haemorrhagic than Senec. [Clarke], [Boericke].
• Staphisagria — Honeymoon cystitis, cutting urethral pain after coitus; mental mortification; urinary stronger than uterine [Kent], [Clarke].
• Chimaphila — Tenacious vesical catarrh with scalding; must stand and lean forward; not specifically cyclic with menses [Boger], [Clarke].
• Bryonia — Suppressed menses with dry, hard cough and stitching chest pains; aggravated motion; less urinary irritability [Farrington].
• Ferrum — Menorrhagia in chlorotic girls with flushing and weakness; no bladder neck keynote [Clarke].

• Complementary: Puls. (restores menstrual rhythm in mild, weepy subjects while Senec. covers vesical/sacral drag) [Clarke]; Ferr. (anaemia) [Clarke]; Caul. (spasmodic element) [Farrington].
• Follows well: Acon. when chill/fright has suppressed the flow; Nux-v. when dietary/stimulant excess irritates bladder premenstrually [Clarke], [Hughes].
• Precedes well: Trill., Sabina in residual haemorrhagic tendencies; Sep. in chronic pelvic relaxation after acute irritability subsides [Boericke], [Clarke].
• Antidotes (drug effects/overreaction): Camph., Nux-v. by tradition [Boericke].
• Compatible: Cimic., Viburn-op., Gossypium in uterine functional disorders (different pain/tonicity profiles) [Farrington], [Hale].
• Inimical: None noted specifically in the classical sources.

• Indications — Pre-menstrual urinary frequency/smarting with sacral aching; delayed/suppressed menses; dysmenorrhoea in pale, easily-chilled girls; vicarious chest symptoms when periods are checked; menorrhagia in chlorotics with backache [Clarke], [Hale], [Boericke].
• Potency & Repetition — Low to mid potencies (Ø/3x/6x) when aiming at local pelvic/vesical irritability; 30C when the cyclic polarity is marked with mental fretfulness; higher potencies episodically at the outset of the pre-menstrual week. Repeat according to relief of nocturia and sacral pain; avoid needless dosing once the flow is established [Boericke], [Dewey], [Hale].
• Adjuncts — Keep warm, especially feet; avoid chills and stimulants; schedule gentle walking after onset of flow; warm Sitz over sacrum; evening fluids moderate to ease nocturia [Hughes], [Clarke].
• Pearls —
  • “Delayed period with nightly vesical urging; sacral drag; period came freely on Senec. 6x, bladder quiet” [Clinical—Clarke].
  • “Suppressed menses after chill; teasing cough and blood-streaked sputum; Senec. restored uterine action and chest cleared” [Clinical—Hale].
  • “Menorrhagia in chlorotic girl; sacral ache; Senec. with iron dietetics improved colour and moderated flow” [Clinical—Clarke].

Mind

• Mind—Anxiety—menses—before. Key pre-menstrual fretfulness. [Clarke]
• Mind—Irritability—menses—before. Urinary loss of sleep sharpens temper. [Clarke]
• Mind—Weeping—easily—before menses. Puls-like mood but with vesical keynotes. [Clarke]
• Mind—Restlessness—night—urination—from frequent desire. Broken sleep. [Allen]
• Mind—Fear—menses—of being late. Worry that mirrors physiology. [Clarke]
• Mind—Concentration—difficult—before menses—better—when flow begins. Polarity hallmark. [Clarke]

Head

• Head—Heaviness—forehead—menses—before—amel. when menses appear. Clears as flow starts. [Clarke]
• Vertigo—rising—menses—suppressed. Circulatory weakness of chlorosis. [Hale]
• Head—Pain—occiput—with sacral pain—menses—before. Pelvic–spinal reflex. [Hering]
• Head—Congestion—without heat—worse—room, warm—better—open air. Matches general modalities. [Clarke]
• Head—Headache—catamenial—delayed menses. Core rubric for selection. [Clarke]

Urinary

• Urging—frequent—menses—before. Earliest prodrome in Senec. [Clarke]
• Urination—pain—burning—neck of bladder—sensitive. Local hallmark. [Allen], [Clarke]
• Urine—scanty—night—menses—before. Nocturia with scant relief. [Clarke]
• Bladder—tenesmus—catarrhal—chill after getting feet wet. Aetiologic clue. [Hughes]
• Urination—frequent—cold—aggravates; warmth—ameliorates. Modal pair. [Clarke]
• Sleep—interrupted—urination—from frequent desire. Carries to Sleep section. [Allen]

Female

• Menses—delayed—urinary symptoms—with. Defining nexus. [Clarke]
• Menses—suppressed—cough/haemoptysis—with. Vicarious outlet. [Clarke], [Hale]
• Dysmenorrhoea—dragging to groins and thighs—better—flow—when. Relief on onset. [Hering]
• Menorrhagia—chlorotic girls. Bright, exhausting flow. [Clarke]
• Leucorrhoea—yellow—menses—before—vesical irritability—with. Cycle-linked discharge. [Hering]
• Abortion—threatened—early months—vesical irritability—with. Conservative, rest + warmth + Senec. [Hale]

Chest / Respiration

• Cough—menses—suppressed—with. Vicarious menstruation rubric. [Clarke]
• Haemoptysis—catamenial—menses—suppressed. Diagnostic pointer. [Clarke], [Hale]
• Voice—hoarseness—menses—suppressed. Laryngeal mirror of uterus. [Clarke]
• Respiration—oppression—room, warm—aggravates—open air—ameliorates. Matches generalities. [Clarke]
• Chest—tightness—better—menses—beginning—when. Polarity again. [Clarke]

Back

• Pain—sacral region—menses—before/during—warmth—ameliorates. Senecio’s back signature. [Hering], [Clarke]
• Pain—lumbar—standing—aggravates—sitting on hard seat—aggravates. Pelvic congestion. [Boger]
• Pain—extends—to groins and thighs—catamenial. Dragging quality. [Hering]
• Weakness—back—catamenial—girls—chlorotic. Constitutional tone. [Clarke]
• Pain—back—better—flow—when. Polarity hallmark. [Clarke]

Generalities

• Generalities—chill—after—menses—suppressed by. Aetiologic link. [Hughes], [Clarke]
• Generalities—cold—damp—aggravates; warmth—applications—ameliorates. Modal pair. [Clarke]
• Generalities—exertion—aggravates—standing—aggravates. Pelvic drag worsens. [Boger]
• Generalities—anaemia—chlorosis—girls. Constitution. [Clarke]
• Generalities—menses—before—aggravates—menses—during—ameliorates. Central polarity. [Clarke]
• Sleep—loss of—urination—from—aggravates complaints. Vicious circle. [Allen]

Hale — New Remedies (late 19th c.): primary clinical source on Senecio aureus in uterine/vesical disorders; cyclic relationships.
T. F. Allen — Handbook / Encyclopaedia of Pure Materia Medica (1874–79; 1898): compiled symptoms; urinary neck sensitivity; catamenial relations.
Hering — The Guiding Symptoms of Our Materia Medica (1879–91): sacral drag, catamenial patterns, haemorrhoidal/rectal notes.
Clarke — A Dictionary of Practical Materia Medica (1900): full clinical portrait—pre-menstrual vesical irritability, vicarious chest symptoms, modalities.
Boericke — Pocket Manual of Homoeopathic Materia Medica (1901/1927): keynotes—delayed/suppressed menses, dysmenorrhoea, menorrhagia, threatened abortion.
Hughes — A Cyclopaedia of Drug Pathogenesy (1885–87): physiological and clinical remarks; chill/catarrh aetiology.
Boger — Synoptic Key (1915/1931): generals—pelvic drag, modalities, exertion/sitting aggravation.
Farrington — Clinical Materia Medica (1887): differentials with Puls., Sep., Caul., Cimic.; catamenial chest links.
Kent — Lectures on Homoeopathic Materia Medica (1905): comparative mental and pelvic indications vs Sepia/Puls.
Dewey — Practical Homoeopathic Therapeutics (1901): therapeutic hints for catamenial disorders and anaemic states.
Nash — Leaders in Homoeopathic Therapeutics (1907): chlorotic menses, practical distinctions.
Tyler — Homoeopathic Drug Pictures (1942): portraits of the adolescent/chlorotic patient; comparisons across uterine remedies.